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ChemInform Abstract: Simple and Efficient Preparation of 2,5-Disubstituted Oxazoles via a Metal-Free-Catalyzed Cascade Cyclization.

✍ Scribed by Changfeng Wan; Linfeng Gao; Qiang Wang; Jintang Zhang; Zhiyong Wang

No coin nor oath required. For personal study only.

✦ Synopsis

The iodine‐catalyzed process allows the synthesis of oxazoles (24 examples) from hydrochloride (I) and aldehydes under mild conditions.

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