Silyl enol ethers as protective groups f
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Andrew C. Grosse; Cornelis M. Moorhoff
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Article
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1997
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John Wiley and Sons
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English
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Alkyl 4-bromo-and 4-chloro-3-oxobutanoates were protected as silyl enol ethers. The Arbuzov reaction of these new compounds with triethyl phosphite gave the corresponding silyl enol phosphonates in high yield. Facile deprotection of the silyl group with water gave alkyl 4-(diethoxyphosphinyl)-3-oxob