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ChemInform Abstract: Silyl Enol Ethers as Protective Groups for Alkyl 4-Halo-3- oxobutanoates in the Arbuzov Reaction with Triethyl Phosphite.

โœ Scribed by A. C. GROSSE; C. M. MOORHOFF


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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Silyl enol ethers as protective groups f
โœ Andrew C. Grosse; Cornelis M. Moorhoff ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 246 KB ๐Ÿ‘ 1 views

Alkyl 4-bromo-and 4-chloro-3-oxobutanoates were protected as silyl enol ethers. The Arbuzov reaction of these new compounds with triethyl phosphite gave the corresponding silyl enol phosphonates in high yield. Facile deprotection of the silyl group with water gave alkyl 4-(diethoxyphosphinyl)-3-oxob