Conformation and membrane activity of an
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Elsa Locardi; Stefano Mammi; Evaristo Peggion; Vania Monaco; Fernando Formaggio;
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Article
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1998
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John Wiley and Sons
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English
โ 207 KB
๐ 1 views
We have synthesized by solution-phase methods two analogues of the 11-residue lipopeptaibol antibiotic trichogin GA IV in which the N-terminal n-octanoyl group is replaced either by an N-acetylated 2-amino-2-methyl-L-undecanoic acid or by an N-acetylated h-aminoisobutyric acid. CD, FTIR absorption,