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ChemInform Abstract: Short-Chain Analogues of the Lipopeptaibol Antibiotic Trichogin GA IV: Conformational Analysis and Membrane Modifying Properties.

โœ Scribed by Fernando Formaggio; Cristina Peggion; Marco Crisma; Claudio Toniolo


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
32
Category
Article
ISSN
0931-7597

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Conformation and membrane activity of an
โœ Elsa Locardi; Stefano Mammi; Evaristo Peggion; Vania Monaco; Fernando Formaggio; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 207 KB ๐Ÿ‘ 1 views

We have synthesized by solution-phase methods two analogues of the 11-residue lipopeptaibol antibiotic trichogin GA IV in which the N-terminal n-octanoyl group is replaced either by an N-acetylated 2-amino-2-methyl-L-undecanoic acid or by an N-acetylated h-aminoisobutyric acid. CD, FTIR absorption,