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ChemInform Abstract: SH2 Domains: From Structure to Energetics, a Dual Approach to the Study of Structure—Function Relationships

✍ Scribed by R. A. Grucza; J. M. Bradshaw; K. Fuetterer; G. Waksman

Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
30
Category
Article
ISSN
0931-7597

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SH2 domains: From structure to energetic
SH2 domains: From structure to energetics, a dual approach to the study of structure–function relationships
✍ R. A. Grucza; J. M. Bradshaw; K. Fütterer; G. Waksman 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB 👁 2 views

## C T I O N Src Homology 2 (SH2) domains are protein modules of about 100 amino acids in size which are found in a large number of proteins involved in signal transduction. The function of SH2 domains is to specifically recognize the phosphorylated state of tyrosine residues, thereby allowing SH