2-Alkyl-1-methylquinazolinium hexafluorophosphates 9 are deprotonated by sodium or potassium hydride to afford solutions of 2-alkylidenedihydroquinazolines 10, which were investigated by NMR spectroscopy. Trapping with methanesulfonyl azide (5a) of 10 in situ or subsequent treatment with trifluorome
ChemInform Abstract: Ring Expansion of 2-Alkylidenedihydroquinazolines to Iminodihydro-1,4-benzodiazepines by Methanesulfonyl and Trifluoromethanesulfonyl Azide.
β Scribed by Helmut Quast; Svetlana Ivanova; Eva-Maria Peters; Karl Peters
- Book ID
- 101908306
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 35 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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2-Alkyl-1-methylquinolinium hexafluorophosphates 1 are deprotonated by sodium or potassium hydride to afford solutions of 2-alkylidenedihydroquinolines 2, which are investigated by NMR spectroscopy. 1,3-Dipolar cycloaddition of phenyl azide to 2 yields the spirocyclic products 10. While, at 80Οͺ110 Β°
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