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ChemInform Abstract: Remarkable Acceleration of a Lipase-Catalyzed Reaction by a Thiacrown Ether Additive: Buffer-Free Highly Regioselective Partial Hydrolysis of 4-Acetoxy-2-methylbut-2-enyl Acetate.

✍ Scribed by T. ITOH; K. MITSUKURA; K. KAIHATSU; H. HAMADA; Y. TAKAGI; H. TSUKUBE


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Remarkable Acceleration of a Lipase-Catalyzed Reaction by a Thiacrown Ether Additive: Buffer-Free Highly Regioselective Partial Hydrolysis of 4-Acetoxy-2-methylbut-2-enyl Acetate.

-The efficiency of the lipase-catalyzed partial hydrolysis of the title acetate (I) is significantly enhanced by the presence of 5 mol.% of a thiocrown ether (TCE). Particularly remarkable improvements are observed in Candida rugosa lipase-and Pseudomonas cepacia lipase-catalyzed reactions. -(ITOH, T.;