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ChemInform Abstract: Regioselective Metal-Catalyzed Hydrophosphinylation of Alkynes: Synthesis of Enantiopure α- or β-Substituted Vinylphosphane Oxides.

✍ Scribed by Amelie Duraud; Martial Toffano; Jean-Claude Fiaud


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
41
Category
Article
ISSN
0931-7597

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## Abstract The Rh‐catalyzed asymmetric addition of α‐ (VII) or β‐substituted S‐chelating aldehydes (I), (V) towards terminal alkynes (II) is successfully used as kinetic resolution procedure to afford the corresponding α‐ and β‐substituted enones in up to 90% optical purity.