ChemInform Abstract: Regio- and Stereoselective Synthesis of Oligosaccharides with Acetobromolactose and Acetobromomaltose as Glycosyl Donors via Orthoester Intermediates.
β Scribed by Wei Wang; Fanzuo Kong
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Highly Regio-and Stereoselective Synthesis of Bioactive Oligosaccharides Using 1,2-O-Ethylidene-Ξ±-D-gluco-and -Ξ²-D-Mannopyranose as the Acceptors and Acetobromosugars as the Donors via Orthoester Intermediates.
The coupling of acetobromosugars as glycosyl donors with partially protected or unprotected alkyl glycoside acceptors affords ortho esters such as (III) in high yields and excellent regioselectivities. They rearrange as either partially or fully protected compounds with high selectivity to 1β6 and 1