ChemInform Abstract: Reaction of Amides with Nitric Oxide (NO).

✍ Scribed by T. ITOH; K. NAGATA; Y. MATSUYA; M. MIYAZAKI; A. OHSAWA

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 28 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199743066

✦ Synopsis

Reaction of Amides with Nitric Oxide (NO).

-The reaction of a variety of amides (13 examples) with NO is studied in detail in order to get insight in nitrosation reactions of amides in biological media. The reaction is accelerated by addition of oxygen and does not proceed in protic solvents suggesting that nitrosations with NO would occur in the lipophilic site of biological systems. -(ITOH, T.;