Nitrogen-containing five-membered heterocycles, N-methylpyrrole 2, N-methylpyrazole 4, N-methylimidazole 6, 4-methylthiazole 11, N-methylindole 14, benzothiazole 16, N-methylbenzimidazole 18, and benzoxazole 20 were lithiated with BuLi and LDA in THF and reacted with the polymerization-resistant 1,2
ChemInform Abstract: Reaction of a Polymerization-Resistant 1,2-Dithiolane with Lithiated Nitrogen Heterocycles.
β Scribed by M. TAZAKI; T. HIEDA; H. MAEDA; S. NAGAHAMA; A. JYO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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Lithiated furans have been found to cleave the S-S bond of polymerization-resistant 1,2dithiolanes to give the ring opened products in good yields. In the case of lithiated benzofuran, the excess reagent reacted with the normal product to give a mixture. Lithiated dihydrofuran and dihydropyran gave
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