ChemInform Abstract: Rational Catalysis Design on the Basis of Mechanistic Understanding: Highly Efficient Pd-Catalyzed Cyanation of Aryl Bromides with NaCN in Recyclable Solvents.

✍ Scribed by Alexander V. Ushkov; Vladimir V. Grushin

• Book ID: 102068496
• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 30 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201151065

✦ Synopsis

Abstract

The efficient and general Pd‐catalyzed aromatic cyanation procedure employs, NaCN — the most preferred cyanide source — in recyclable and low‐boiling solvents with minimal quantities of inexpensive, nontoxic promoters.