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ChemInform Abstract: Radiosynthesis of (Tetrazoyl-11C)irbesartan, a Non-Peptidic Angiotensin II Antagonist.

✍ Scribed by M. PONCHANT; S. DEMPHEL; F. HINNEN; C. CROUZEL

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199751150

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✦ Synopsis

Radiosynthesis of (Tetrazoyl-11C)irbesartan, a Non-Peptidic Angiotensin II Antagonist. -A one-pot procedure for labeling the tetrazole moiety is developed. The resulting irbesartan (V) is not suitable for studying myocardial angiotensin II receptor with positron-emission tomography.

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