✦ LIBER ✦

ChemInform Abstract: Radical-Mediated Construction of Cyclopentane with Concurrent Formation of a Well-Defined Quaternary Center.

✍ Scribed by Qiang Zhu; Li-Xin Qiao; Yikang Wu; Yu-Lin Wu

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199934208

No coin nor oath required. For personal study only.

✦ Synopsis

Radical-Mediated Construction of Cyclopentane with Concurrent

Formation of a Well-Defined Quaternary Center.

-With a view to the synthesis of cyclopentane precursors for diterpene compound (VIII), a novel radical-mediated cyclization reaction of cyclic acetals (I) and (V) is developed which gives cyclopentanes with high yields and diastereoselectivities. These cyclic acetals give much better results than an approach with an open chain precursor. Although the products have not the desired configuration for the target diterpene, compounds (III) and (VII) can serve as very useful building blocks for other synthetic targets. -(ZHU,

📜 SIMILAR VOLUMES

ChemInform Abstract: Formation of Quater

ChemInform Abstract: Formation of Quaternary Carbon Center with a Trifluoromethyl Group Using a Pd-Catalyzed Allylation Reaction.

✍ Kazuyuki Sato; Yu Takiguchi; Yosuke Yoshizawa; Kayoko Iwase; Yoshie Shimizu; Ats 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 44 KB 👁 1 views

ChemInform Abstract: Construction of Chi

ChemInform Abstract: Construction of Chiral Quaternary Carbon Centers by Catalytic Enantioselective Radical-Mediated Allylation of α-Iodolactones Using Allyltributyltin in the Presence of a Chiral Lewis Acid.

✍ M. MURAKATA; T. JONO; Y. MIZUNO; O. HOSHINO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

ChemInform Abstract: Formation of Quater

ChemInform Abstract: Formation of Quaternary Carbon Centers by Highly Regioselective Hydroformylation with Catalytic Amounts of a Reversibly Bound Directing Group.

✍ Yusuke Ueki; Hideto Ito; Ippei Usui; Bernhard Breit 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 40 KB

ChemInform Abstract: Single and Double R

ChemInform Abstract: Single and Double Ring Closing Metathesis in the Formation of Dihydropyrans and Bisoxacyclic Systems with a Quaternary Center.

✍ Bernd Schmidt; Holger Wildemann 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

ChemInform Abstract: Fluorinated Aromati

ChemInform Abstract: Fluorinated Aromatic Ketones as Nucleophiles in the Asymmetric Organocatalytic Formation of C—C and C—N Bonds: A Facile Route to the Construction of Fluorinated Quaternary Stereogenic Centers.

✍ Yujun Zhao; Yuanhang Pan; Hongjun Liu; Yuanyong Yang; Zhiyong Jiang; Choon-Hong 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 40 KB

ChemInform Abstract: “One-Pot” Access to

ChemInform Abstract: “One-Pot” Access to 4H-Chromenes with Formation of a Chiral Quaternary Stereogenic Center by a Highly Enantioselective Iminium-Allenamine Involved Oxa-Michael—Aldol Cascade.

✍ Chunliang Liu; Xinshuai Zhang; Rui Wang; Wei Wang 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 38 KB 👁 2 views

## Abstract Even alkyl alkynals (IV) are converted with excellent enantioselectivities using higher catalyst loading and a longer reaction time.