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ChemInform Abstract: Pyrrolidine-Camphor Derivative as an Organocatalyst for Asymmetric Michael Additions of α,α-Disubstituted Aldehydes to β-Nitroalkenes: Construction of Quaternary Carbon-Bearing Aldehydes under Solvent-Free Conditions.

✍ Scribed by Chihliang Chang; Ssu-Hsien Li; Raju Jannapu Reddy; Kwunmin Chen


Publisher
John Wiley and Sons
Year
2009
Weight
33 KB
Volume
40
Category
Article
ISSN
0931-7597

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Abstract

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Pyrrolidine-Camphor Derivative as an Org
✍ Chihliang Chang; Ssu-Hsien Li; Raju Jannapu Reddy; Kwunmin Chen 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 184 KB 👁 2 views

## Abstract magnified image A novel pyrrolidine‐camphor organocatalyst **3** was designed, synthesized and proven to be an efficient catalyst for the asymmetric Michael reaction. Treatment of α,α‐disubstituted aldehydes with β‐nitroalkenes in the presence of 20 mol% organocatalyst **3** and 20 mol