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ChemInform Abstract: Pyrrole Acylation for the Synthesis of 2-Bromo-6-(2-pyrrolyl)pyridine and Subsequent Cross-Coupling Reactions.

✍ Scribed by Chuanjun Song; Yan Liu; Peng Zhao; Xuelian Sun; Wenjia Li; Hui Liu; Junbiao Chang


Publisher
John Wiley and Sons
Year
2011
Weight
42 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A previously developed pyrrole acylation process using carboxylic acids and TFAA is successfully applied as the initial step in the synthesis of the starting material (VII).


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ChemInform Abstract: A New Method for th
✍ Chuanjun Song; Peng Zhao; Yan Liu; Hui Liu; Wenjia Li; Shuai Shi; Junbiao Chang πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB

## Abstract Key steps of the title synthesis are the previously developed pyrrole acylation method with monoethyl succinate (II) and the Suzuki cross coupling reaction of 3‐chloro‐6‐pyrrolylpyridazine (V) with arylboronic acids.