ChemInform Abstract: Pursuit of Optimal Carbohydrate-Based Anticancer Vaccines: Preparation of a Multiantigenic Unimolecular Glycopeptide Containing the Tn, MBr1 and Lewisy Antigens.
β Scribed by Jennifer R. Allen; Christina R. Harris; Samuel J. Danishefsky
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
Dedicated to Professor Steven V. Ley on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metas
on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metastasis, [5] and hence its expression i