ChemInform Abstract: Process Development of a Platelet Aggregation Inhibitor.
β Scribed by Atsuhiko Zanka
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Process Development of a Platelet Aggregation Inhibitor.
-An improved, large-scale synthesis of the platelet aggregation inhibitor (V) is described. This method involves the temporary transformation of an in situ prepared aminopiperazine to a hydrazone, allowing efficient separation of zinc salt by-products from the system. -(ZANKA, ATSUHIKO; Org. Process
π SIMILAR VOLUMES
Tropane-Based Amino Acids for Peptide Structure-Function Studies: Inhibitors of Platelet Aggregation. -Compound (VIII) and three other analogues prepared earlier, which are conformationally constrained amino acids, are incorporated into analogues of reported inhibitors of platelet aggregation (no yi