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ChemInform Abstract: Process Development of a Platelet Aggregation Inhibitor.

✍ Scribed by Atsuhiko Zanka


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Process Development of a Platelet Aggregation Inhibitor.

-An improved, large-scale synthesis of the platelet aggregation inhibitor (V) is described. This method involves the temporary transformation of an in situ prepared aminopiperazine to a hydrazone, allowing efficient separation of zinc salt by-products from the system. -(ZANKA, ATSUHIKO; Org. Process


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ChemInform Abstract: Tropane-Based Amino
✍ P. E. THOMPSON; D. L. STEER; M.-I. AGUILAR; M. T. W. HEARN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 1 views

Tropane-Based Amino Acids for Peptide Structure-Function Studies: Inhibitors of Platelet Aggregation. -Compound (VIII) and three other analogues prepared earlier, which are conformationally constrained amino acids, are incorporated into analogues of reported inhibitors of platelet aggregation (no yi