✦ LIBER ✦
ChemInform Abstract: Probing the Importance of Spacial and Conformational Domains in Captopril Analogues for Angiotensin Converting Enzyme Activity.
✍ Scribed by S. HANESSIAN; U. REINHOLD; M. SAULNIER; S. CLARIDGE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Probing the Importance of Spacial and Conformational Domains in Captopril Analogues for Angiotensin Converting Enzyme Activity.
-An improved large-scale synthesis of 4,5-methano-prolines (IV) and (V) and the enzymatic activity of the corresponding N-(3-mercapto-2-methyl-propionyl) derivatives, e.g. (VIII), as ACE-inhibitors is described. -(HANESSIAN, S.;