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ChemInform Abstract: Preparation of New 5-Aroylamino Substituted 3-Nicotinoyl/Isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with Anti-inflammatory Activity.

✍ Scribed by Silvia Schenone; Olga Bruno; Angelo Ranise; Francesco Bondavalli; Walter Filippelli; Giuseppe Falcone; Brunella Piucci; Salvatore Sorrentino

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199922132

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✦ Synopsis

Preparation

of New 5-Aroylamino Substituted 3-Nicotinoyl/Isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with Antiinflammatory Activity.

-All the title compounds (V), especially (Vb) and (Vc), exhibit anti-inflammatory activity and are devoid of antipyretic properties.

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