ChemInform Abstract: Preparation of 4-O-Acetyl-2-deoxy-2H-N-acetylneuraminic Acid.
โ Scribed by B. P. BANDGAR
- Book ID
- 112035371
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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A synthesis of N-acetylneuraminic acid (1) and of N-acetyl-4-epineuraminic acid (2, R = H) from 2-acetamido-4,6-O-benzylidene-l,2-dideoxy-1 -nitro-D-mannopyranose (3) and 2-acetamido-l,2-dideoxy-4,6-0-isopropylidene-l -nitro-D-mannopyranose (4), respectively, is described. Michael addition of 3 and