𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Preparation and Application of α-Bromomono- and -bisdifluoromethoxyacetophenones in the Course of Synthesis of Polymethyleneimidazoles Containing a Bridge Nitrogen Atom.

✍ Scribed by A. M. DEMCHENKO; K. G. NAZARENKO; D. V. FEDYUK; YU. A. FIALKOV; S. V. SHELYAZHENKO; L. M. YAGUPOL'SKII

Publisher
John Wiley and Sons
Year
2010
Weight
41 KB
Volume
29
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Preparation and Application of α-Bromomono-and bisdifluoromethoxyacetophenones in the Course of Synthesis of Polymethyleneimidazoles Containing a Bridge Nitrogen Atom. -The synthesis of the title difluoromethoxyacetophenones (III) is easily achieved by reaction of freon-22 (II) with mono-or dihydroxyacetophenone. Their bromoacetyl derivatives (V) undergo coupling with heterocyclic enamines to provide access to fused imidazole derivatives [cf. (VII), (IX)]. Moreover, the bromoacetophenone (Va) is used as reagent for the N-alkylation of various pyridine derivatives [→ (XI)]. -(DEMCHENKO, A. M.; NAZARENKO,

📜 SIMILAR VOLUMES

ChemInform Abstract: Design and Synthesi
ChemInform Abstract: Design and Synthesis of N-Nonpolar Nucleobase Dipeptides: Application of the Ugi Reaction for the Preparation of Dipeptides Having Fluoroarylalkyl Groups Appended to the Nitrogen Atom.
✍ Biplab Kumar Das; Norio Shibata; Yoshio Takeuchi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v