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ChemInform Abstract: Practical Modifications and Applications of the Sharpless Asymmetric Aminohydroxylation in the One-Pot Preparation of Chiral Oxazolidin-2-ones.

โœ Scribed by Nancy S. Barta; Daniel R. Sidler; Kara B. Somerville; Steven A. Weissman; Robert D. Larsen; Paul J. Reider


Publisher
John Wiley and Sons
Year
2001
Weight
31 KB
Volume
32
Category
Article
ISSN
0931-7597

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Application of Sharpless asymmetric epox
โœ Hong-yu Tian; Bao-guo Sun; Li-wei Tang; Hong-lin Ye ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 207 KB

## Abstract Optically active 2,3โ€epoxyhexanol obtained from Sharpless asymmetric epoxidation (AE) was regioselectively reduced to 1,3โ€hexandiol or 1,2โ€hexandiol. 1,3โ€Hexandiol was converted to 3โ€mesyloxyhexyl acetate. The following reaction with CH~3~SK gave 3โ€methylthiohexanol, which was oxidized