Application of Sharpless asymmetric epox
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Hong-yu Tian; Bao-guo Sun; Li-wei Tang; Hong-lin Ye
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Article
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2010
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John Wiley and Sons
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English
โ 207 KB
## Abstract Optically active 2,3โepoxyhexanol obtained from Sharpless asymmetric epoxidation (AE) was regioselectively reduced to 1,3โhexandiol or 1,2โhexandiol. 1,3โHexandiol was converted to 3โmesyloxyhexyl acetate. The following reaction with CH~3~SK gave 3โmethylthiohexanol, which was oxidized