ChemInform Abstract: Practical Enantiodivergent Syntheses of Both Enantiomers of Carbovir, 1592U89 and Six-Membered Ring Analogues.

✍ Scribed by H. F. OLIVO; J. YU

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 35 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199822156

✦ Synopsis

Practical Enantiodivergent Syntheses of Both Enantiomers of Carbovir, 1592U89 and Six-Membered Ring Analogues.

-The usefulness of the known, optically active hydroxylactones (I), obtained from an enzymatical resolution, for the synthesis of the title compounds such as (VIII) and (X) is shown. The enantiomers can be prepared in an identical fashion starting from the antipodes of (I). -(OLIVO, H. F.;