A metabolite of Aripiprazole (1), 7-[4-[4-(2,3-dichloro.4-hydroxyphenyl)-l-pipetazinyl]butoxy]-3,4-&~ydto-2(IH)-quinolino~ (2), was prepared by the coupling reaction of 1-(4-be, nzyloxy-2,3-dichlorophenyl)pipengine (11) with 7-(4-Β’.hlombutoxy)-3,4-dihydm-2(1H)-quinolinone ( 16). The gelladium-cataly
β¦ LIBER β¦
ChemInform Abstract: Practical Application of the Palladium-Catalyzed Amination in Phenylpiperazine Synthesis: An Efficient Synthesis of a Metabolite of the Antipsychotic Agent Aripiprazole.
β Scribed by S. MORITA; K. KITANO; J. MATSUBARA; T. OHTANI; Y. KAWANO; K. OTSUBO; M. UCHIDA
- Book ID
- 101864278
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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