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ChemInform Abstract: Potential Antineoplastics. Synthesis and Cytotoxicity of Certain 4-Chloro-3-(2-chloroethyl)-2-methylquinolines and Related Derivatives.

✍ Scribed by E.-S. A. M. BADAWEY; T. KAPPE

Publisher: John Wiley and Sons
Year: 2010
Weight: 36 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199806179

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✦ Synopsis

Potential Antineoplastics. Synthesis and Cytotoxicity of Certain 4-Chloro-3-(2-chloroethyl)-2-methylquinolines and Related Derivatives. -The synthesis of the title quinolines (IV) and their conversion into some thieno-[cf. (V)], furo-[cf. (VI)] and pyrroloquinolines [cf. (VIII), (IX)] is described. The obtained heterocycles are evaluated for their toxicity and cytotoxicity in vitro. -(BADAWEY, E.-S.

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