ChemInform Abstract: Potent Antiinflammatory 3-Thiazole-4(5)-acetic Acids of 1,2-Benzisothiazole.
β Scribed by P. K. SHARMA; S. N. SAWHNEY
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The synthesis of two diastereomers of the title compound involves the coupling of 5βlithiated 2β(1,1βdimethoxyethyl)thiazole (VI) with a Weinreb amide (V) derived from gluconolacetone, followed by asymmetric reduction of the ketone functionality.
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