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ChemInform Abstract: pKa Values of 3-Thioxo-1,2-dithiole-4- and -5-carboxylic Acids and of 3-Oxo-1,2-dithiole-4- and -5-carboxylic Acids in Aqueous Solution at 298 K.

โœ Scribed by M. CHOLLET; J. L. BURGOT


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Excha
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Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi