ChemInform Abstract: Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. Part 1. 2(S)-Methyl Piperazine as a Key Pharmacophore Element.

Piperazine-Based CCR5 Antagonists as HIV

Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. Part 3. Synthesis, Antiviral and Pharmacokinetic Profiles of Symmetrical Heteroaryl Carboxamides (VIII).

✍ Jayaram R. Tagat; et al. et al. 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 122 KB 👁 1 views

ChemInform Abstract: Antagonists of the

ChemInform Abstract: Antagonists of the Human CCR5 Receptor as Anti-HIV-1 Agents. Part 2. Structure—Activity Relationships for Substituted 2-Aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino] -4-(piperidin-1-yl)butanes.

✍ Paul E. Finke; et al. et al. 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 27 KB 👁 2 views

ChemInform Abstract: Antagonists of the

ChemInform Abstract: Antagonists of the Human CCR5 Receptor as Anti-HIV-1 Agents. Part 4. Synthesis and Structure—Activity Relationships for 1-[N-(Methyl)-N-(phenylsulfonyl)amino] -2-(phenyl)-4-(4-(N-(alkyl)-N- (benzyloxycarbonyl)amino)piperidin-1-yl)butanes.

✍ Paul E. Finke; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

ChemInform Abstract: A Novel Synthetic A

ChemInform Abstract: A Novel Synthetic Approach to Very Late Antigen-4 Antagonist trans-4-[1-[ [2,5-Dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl]acetyl] -(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid (VIII) via tert-Butyl trans-[(4S)-Methoxy-(2S)-pyrrolidinylmethoxy] Cyclohexanecarboxylate (VI) as a Key Intermediate.

✍ Jun Chiba; Nobuo Machinaga 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 31 KB

A Novel Synthetic Approach to Very Late Antigen-4 Antagonist trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl]acetyl]--(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid (VIII) via tert-Butyl trans-[(4S)-Methoxy-(2S)-pyrrolidinylmethoxy] Cyclohexanecarboxylate (VI) as

ChemInform Abstract: Novel Stereoselecti

ChemInform Abstract: Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D1 Antagonist (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo [d]naphth[2,1-b]azepin-12-ol (Sch 39166). Part 1. Aziridinium Salt Based Syntheses.

✍ R. W. DRAPER; D. HOU; R. IYER; G. M. LEE; J. T. LIANG; J. L. MAS; W. TORMOS; E. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 43 KB 👁 1 views

ChemInform Abstract: Novel Stereoselecti

ChemInform Abstract: Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D1 Antagonist (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo [d]naphth[2,1-b]azepin-12-ol (Sch 39166). Part 2. L-Homophenylalanine-Based Syntheses.

✍ R. W. DRAPER; D. HOU; R. IYER; G. M. LEE; J. T. LIANG; J. L. MAS; E. J. VATER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 44 KB 👁 2 views

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