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ChemInform Abstract: Peptide Nucleic Acids: Potential as Antisense and Antigene Drugs

✍ Scribed by Anne B. Eldrup; Peter E. Nielsen

Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Peptide Nucleic Aci
ChemInform Abstract: Peptide Nucleic Acids
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Monofunctionally trans-Diammine Platinum
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A solid-phase approach is described that provides facile access to monofunctionally trans-PtII-modified PNA oligomers of arbitrary sequence for potential use both in antigene and antisense strategies. The approach includes the synthesis of a platinated building block 1 and its subsequent incorporati