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ChemInform Abstract: Pd-Catalyzed Cyclization Reactions of Acetylene-Containing α-Amino Acids.

✍ Scribed by L. B. WOLF; K. C. M. F. TJEN; F. P. J. T. RUTJES; H. HIEMSTRA; H. E. SCHOEMAKER


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
29
Category
Article
ISSN
0931-7597

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Palladium-Catalyzed Cyclization Reaction
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Enantiomerically pure acetylene-containing aamino acids were used as versatile starting materials for the synthesis of a variety of heterocycles via Pd-mediated cyclization reactions. Depending on the protecting group strategy, both the carboxylate and the amine function of the amino acids could par