ChemInform Abstract: Pd-Catalyzed Cross-Coupling of Carboxylic Acids with Nitroethane via Combination of Decarboxylation and Dehydrogenation.
✍ Scribed by Min Zhang; Jun Zhou; Jian Kan; Min Wang; Weiping Su; Maochun Hong
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 42 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The first metal‐catalyzed methodology for the cross‐coupling of a broad range of benzoic acids with nitroethane furnishing exclusively (E)‐β‐nitrostyrenes is described.
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## Abstract A variety of unsymmetrical alkynes (III) is readily prepared by a highly efficient Pd(O‐Ac)~2~‐catalyzed decarboxylative cross‐coupling of boronic acids (I) with acids (II) in the presence of Ag~2~O as oxidant.
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