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ChemInform Abstract: Parathyroid Hormone and Parathyroid Hormone-Related Protein: Model Systems for the Development of an Osteoporosis Therapy

✍ Scribed by Dale F. Mierke; Maria Pellegrini


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
30
Category
Article
ISSN
0931-7597

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Parathyroid hormone-related protein (PTHrP) is the cause of humoral hypercalcaemia of malignancy and interacts with parathyroid hormone (PTH) receptors. Breast cancer cells produce PTHrP in vitro and in vivo. The breast cancer cell line MCF-7, which products PTHrP and expresses PTHrP receptors, prol