ChemInform Abstract: Palladium-Catalyzed Regioselective Carbonylation of 2,3-Dienylamines to α-Vinylacrylamides.

✍ Scribed by Y. IMADA; G. VASAPOLLO; H. ALPER

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199716093

✦ Synopsis

Palladium-Catalyzed

Regioselective Carbonylation of 2,3-Dienylamines to α-Vinylacrylamides.

-The insertion of carbon monoxide occurs in a regioselective manner at the central sp carbon of the allene unit without forming other isomers. The less-hindered amines (I) and (IV) are carbonylated smoothly in the presence of 0.5 mol% of palladium catalyst. The highly substituted amines (VI) and (VIII) undergo carbonylation when 2 mol% of palladium catalyst is used. -(IMADA, Y.; VASAPOLLO, G.; ALPER, H.;