ChemInform Abstract: Palladium-Catalyzed Nucleophile-Alkyne-α,β-Unsaturated Carbonyl Coupling Through Tandem Nucleopalladation and Conjugate Addition.
✍ Scribed by Z. WANG; X. LU
- Book ID
- 112035866
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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A regioselective divalent palladium-catalyzed tandem coupling reaction of allenoic acids with a,b-unsaturated carbonyl compounds was developed. The reaction involves intramolecular oxypalladation of an allene, followed by insertion of the a,b-unsaturated carbonyl compound and protonolysis of the C P
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