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ChemInform Abstract: Palladium-Catalyzed Coupling Reactions of Bromobenzaldehydes with 3,4-Di(tert-butyldimethylsilyloxy)-1-alkene to (3,4-Dihydroxyalkenyl)benzaldehydes in the Synthesis of Lipoxin Analogues.

✍ Scribed by J. NOKAMI; A. FURUKAWA; Y. OKUDA; A. HAZATO; S. KUROZUMI

Publisher: John Wiley and Sons
Year: 2010
Weight: 35 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199824197

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✦ Synopsis

Palladium-Catalyzed

Coupling Reactions of Bromobenzaldehydes with 3,4-Di(tert-butyldimethylsilyloxy)-1-alkene to (3,4-Dihydroxyalkenyl)benzaldehydes in the Synthesis of Lipoxin Analogues.

-Preliminary biological activities of lipoxin analogues of type (VI) and (VIII) are evaluated using in vitro systems. Both compounds show chemotaxis inhibition activity. -(NOKAMI,

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