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ChemInform Abstract: Oxidative Heterocyclization of 2-Alkynylbenzaldehydes with 1,2-Phenylenediamine.

✍ Scribed by Gerald Dyker; Wolfgang Stirner; Gerald Henkel


Publisher
John Wiley and Sons
Year
2001
Weight
37 KB
Volume
32
Category
Article
ISSN
0931-7597

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Oxidative Heterocyclization of 2-Alkynyl
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quinolines (8) or isoindolo[2,1-a]quinoxalines (9) depending on the influence of additional substituents at the alkyne. Scheme 1. Condensation of phenylenediamine 2 with bis(aldehyde) 1 under neutral and under oxidative conditions Scheme 2. Reaction conditions: a. 1 mol-% Pd(OAc) 2 , 2 mol-% PPh 3

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