Organotin(IV) enamines as selective reag
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Makoto Yasuda; Junji Morimoto; Ikuya Shibata; Akio Baba
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Article
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1997
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Elsevier Science
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French
⚖ 123 KB
Effective coupling of tin enamines I and ct-haloaldehydes 2 gave 2,4-disubstituted pyrroles in high yields at room temperature even under aqueous conditions. The reaction with 2bromoaeetophenone gave 3,4-disubstituted pyrroles, while the addition of HMPA changed the selectivity to afford the 2,4-iso