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ChemInform Abstract: Organotin(IV) Enamines as Selective Reagents: Coupling with α-Halocarbonyls for the Synthesis of Substituted Pyrroles.

✍ Scribed by M. YASUDA; J. MORIMOTO; I. SHIBATA; A. BABA


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
28
Category
Article
ISSN
0931-7597

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Organotin(IV) enamines as selective reag
✍ Makoto Yasuda; Junji Morimoto; Ikuya Shibata; Akio Baba 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 123 KB

Effective coupling of tin enamines I and ct-haloaldehydes 2 gave 2,4-disubstituted pyrroles in high yields at room temperature even under aqueous conditions. The reaction with 2bromoaeetophenone gave 3,4-disubstituted pyrroles, while the addition of HMPA changed the selectivity to afford the 2,4-iso