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ChemInform Abstract: Organocatalytic Direct Asymmetric Vinylogous Michael Reaction of an α,β-Unsaturated γ-Butyrolactam with Enones.

✍ Scribed by Yong Zhang; Yong-Liang Shao; Hai-Sen Xu; Wei Wang


Publisher
John Wiley and Sons
Year
2011
Weight
33 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The title reaction allows an efficient and highly stereoselective access to substituted lactams of type (III).


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Organocatalytic Direct Vinylogous Michae
✍ Xin Feng; Hai-Lei Cui; Shi Xu; Li Wu; Prof. Dr. Ying-Chun Chen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 1 views

Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/chem.201001350. Scheme 1. Direct vinylogous Michael addition to multifunctional adducts for scaffold diversity synthesis.