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ChemInform Abstract: Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters.

✍ Scribed by Wen-Bing Chen; Zhi-Jun Wu; Jing Hu; Lin-Feng Cun; Xiao-Mei Zhang; Wei-Cheng Yuan

Publisher: John Wiley and Sons
Year: 2011
Weight: 54 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201136109

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✦ Synopsis

Abstract

The reaction allows the preparation of various functionalized target compounds with good yields and enantioselectivities, albeit in many cases with moderate diastereoselectivities.

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