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ChemInform Abstract: Optimization of the Suzuki Coupling Reaction in the Synthesis of 2-[(2-Substituted)phenyl]pyrrole Derivatives.

✍ Scribed by Marija Aleskovic; Nikola Basaric; Kata Mlinaric-Majerski


Book ID
112043118
Publisher
John Wiley and Sons
Year
2012
Weight
29 KB
Volume
43
Category
Article
ISSN
0931-7597

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Optimization of the Suzuki coupling reac
✍ Marija Alešković; Nikola Basarić; Kata Mlinarić-Majerski 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 233 KB

## Abstract A facile three‐step synthesis of 2‐(2‐aminophenyl)pyrrole (**1**) and 2‐[(2‐aminomethyl)phenyl]pyrrole (**2**) is reported by use of Suzuki coupling of __N__‐Boc‐pyrrol‐2‐yl boronic acid (**3**) and o‐substituted aryl halogenides, followed by hydrogenation. The Pd‐catalyzed cross‐coupli