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ChemInform Abstract: Optically Pure 3,6-Dioxazocan-2-one Derivatives by Intramolecular Cycloaddition of Azidoformates and Their Opening to Substituted α-Amino Ketones.

✍ Scribed by Marco de Santis; Stefania Fioravanti; Lucio Pellacani; Paolo A. Tardella


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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Optically Pure 3,6-Dioxazocan-2-one Deri
✍ Marco de Santis; Stefania Fioravanti; Lucio Pellacani; Paolo A. Tardella 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 216 KB

Azidoformates derived from chiral enol ethers, when hydrolysis of 7 gives a single derivative of 2-aminocyclohexanone. irradiated, give 3,6-dioxazocan-2-one derivatives 7 by a highly diastereoselective intramolecular cycloaddition. The [a] Dipartimento di Chimica dellЈUniversita `di Roma "La Sapienz