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ChemInform Abstract: Optical Resolution and Absolute Stereochemistry of trans-2,5-Dimethyl- 1-phenyl-1-silacyclopentane.

โœ Scribed by H.-S. DANG; B. P. ROBERTS; D. A. TOCHER


Book ID
112022298
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
26
Category
Article
ISSN
0931-7597

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The racemic title bicycle (V) undergoes spontaneous resolution on crystallization from chloroform or acetone. The absolute configuration of the obtained enantiopure product (16-44% e.e.) is determined by comparison with (S)-(V) derived from (S)-Ser-OMe (I). Mutarotation due to partial conversion of