ChemInform Abstract: One-Step Syntheses of the Pyrrolo[3,4-b]indole and Pyrrolo[2,3-b]indole Ring Systems from 3-Nitroindoles.

✍ Scribed by E. T. PELKEY; G. W. GRIBBLE

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199804113

✦ Synopsis

One-Step Syntheses of the Pyrrolo[3,4-b]indole and Pyrrolo[2,3b]indole Ring Systems from 3-Nitroindoles. -3-Nitroindoles like (I) are converted into the corresponding protected derivatives (III). The compounds (III) react with isocyanides (IV) and (VI) under the Barton-Zard pyrrole synthesis conditions either to pyrrolo[3,4-b]indoles (V) and (VIII) or to pyrrolo[2,3-b]indole (VII). -(