ChemInform Abstract: One-Pot Conversion of Aromatic Bromides and Aromatics into Aromatic Nitriles.

✍ Scribed by Sousuke Ushijima; Hideo Togo

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 23 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201043074

✦ Synopsis

Abstract

Various bromoarenes and p‐iodotoluene can be efficiently converted to nitriles through a one‐pot sequence including lithiation, reaction with DMF and subsequent oxidation with iodine in the presence of ammonia.