## Abstract Aminoglutethimide [3‐(4‐aminophenyl)‐3‐ethylpiperidine‐2,6‐dione] has been used clinically in the treatment of metastatic breast carcinoma. Inhibition of tumor growth is due to interference with estrogen biosynthesis. However, its action is not specific and its metabolism gives rise to
✦ LIBER ✦
ChemInform Abstract: On the Relocation of the Amino Functionality to the Ethyl Side Chain in Aminoglutethimide: Synthesis and Aromatase-Inhibitory Activity of 3- (2′-N,N-Diethylamino)ethyl-3-phenylpiperidine-2,6-dione.
✍ Scribed by G. A. MONIZ; G. B. HAMMOND
- Book ID
- 101857484
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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