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ChemInform Abstract: O-Substituted Alkyl Aldehydes for Rhodium-Catalyzed Intermolecular Alkyne Hydroacylation: The Utility of Methylthiomethyl Ethers.

✍ Scribed by Scott R. Parsons; Joel F. Hooper; Michael C. Willis


Publisher
John Wiley and Sons
Year
2011
Weight
36 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Rhodium-Catalyzed I
✍ Carlos Gonzalez-Rodriguez; Scott R. Parsons; Amber L. Thompson; Michael C. Willi 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 69 KB

## Abstract The Rh‐catalyzed asymmetric addition of α‐ (VII) or β‐substituted S‐chelating aldehydes (I), (V) towards terminal alkynes (II) is successfully used as kinetic resolution procedure to afford the corresponding α‐ and β‐substituted enones in up to 90% optical purity.