Various pyridinium salts (see 1 ± 9) have been tested as catalysts for the condensation step in the phosphoramidite approach of oligonucleotide synthesis. Pyridinium chloride (1) turned out to be the most effective activator, speeding up the condensation tremendously. Pyridinium bromide (2) and 4-me
✦ LIBER ✦
ChemInform Abstract: Nucleotides. Part 62. Pyridinium Salts — An Effective Class of Catalysts for Oligonucleotide Synthesis.
✍ Scribed by Markus Beier; Wolfgang Pfleiderer
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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