ChemInform Abstract: Nucleotides. Part 55. Synthesis and Application of a Novel Linker for Solid-Phase Synthesis of Modified Oligonucleotides.

✍ Scribed by S. R. WALDVOGEL; W. PFLEIDERER

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199818246

✦ Synopsis

Nucleotides. Part 55. Synthesis and Application of a Novel Linker for Solid-Phase Synthesis of Modified Oligonucleotides.

-New linker molecules (I)-(IV) are prepared as alternatives to start oligonucleotide syntheses on solid supports. They have the potential to modify additionally the sugar moiety, i.e. at the 3'-OH position needed for linker bonding. -