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ChemInform Abstract: Nucleophilic Substitution of 4H-Imidazoles — A Key Step in the Synthesis of Fused Imidazoles and New Chromophores.

✍ Scribed by Jens Atzrodt; Rainer Beckert; Wolfgang Guenther; Helmar Goerls


Publisher
John Wiley and Sons
Year
2001
Weight
36 KB
Volume
32
Category
Article
ISSN
0931-7597

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Abstract

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Nucleophilic Substitution of 4H-Imidazol
✍ Jens Atzrodt; Rainer Beckert; Wolfgang Günther; Helmar Görls 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 295 KB 👁 2 views

The electrophilic properties of the 4H-imidazoles 1 and their protonated derivatives 2 permit the introduction of nucleophilic building blocks, as illustrated by reactions of 1 with selected amines. Depending on the nature of the amine and the substituents R 1 on the heterocycle 1, single (3) or dou