ChemInform Abstract: Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L.
β Scribed by Jean-Pierre Falgueyret; Renata M. Oballa; Osamu Okamoto; Gregg Wesolowski; Yves Aubin; Robert M. Rydzewski; Peppi Prasit; Denis Riendeau; Sevgi B. Rodan; M. David Percival
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 28 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors. -A series of 20 1,6-naphthyridines, e.g. (I), is synthesized by amidation of key intermediate (IV) and in case of its halogen analogue (V) by subsequent Stille coupling with stannanes, e.g. (V